The "raw data" or Raw Data file stores all the results of the genetic markers included in our genotyping chip that are measured in the laboratory. It is important to understand that, out of this immense raw reading, only a selection of markers is individually analyzed and validated to form the visual reports of the Koko Genetics platform.
You can conveniently download this file by accessing your private account under Settings > Raw Data. Once downloaded, it allows you to easily search for the result of specific markers (whether by their RS identification number or by their position in the genome) and upload it to other genetic interpretation platforms. However, you must keep in mind that this raw data is offered exclusively for informational purposes and should never be used for medical or diagnostic use without the assessment of a veterinary professional.
When you open the document, you will see the biological information distributed in several technical columns. Below, we explain how to interpret each of them:
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ID (Identifier): Refers to the ID of the probes present on our technological array (Axiom™ Canine HD Array). The variants analyzed in this section correspond to single nucleotide polymorphisms (SNPs) and small genetic insertions or deletions.
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Chromosome: Indicates the exact number of the chromosome where the genetic variant is located. Dogs have 38 pairs of autosomal chromosomes (which are indicated by a number from 1 to 38). Sex chromosomes are named with the numbers 39 and 40, while markers located in mitochondrial DNA are listed with the number 42.
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Position: Reflects the exact location of the genetic marker based on our reference genome, CanFam 3.1.
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Genotype: This column contains the results of your pet's genotype for each marker. Genotypes are shown as combinations of pairs of the four DNA nucleotides: A, T, G, and C. Genetic insertions are represented by the letter I and deletions by the letter D. If for any technical reason the genotype of a specific marker could not be determined, the symbol ‘–’ will appear. All this reading is Plus-oriented according to the reference genome CanFam 3.1, from the National Center for Biotechnology Information (NCBI).